Gerald Maurice Edelman 1929 -2014

Gerald Maurice Edelman died in La Jolla California at the age of 84.

Immunologist worldwide recognize him for his contribution to the antibody enigma. Trained in medicine and chemistry his first publication on antibodies established that these molecules can be subjected to urea and sulfhydryl treatment and yield smaller chains as we know now very well but was new in 1959 when first published. For his work on antibody strucuture which e.g. lead to the first sequence of Ig γ-chain he was awarded the Nobel Prize in 1972 together with Rodney R. Porter.

The antibody enigma was only solved by Susumu Tonegawa who showed that recombination of the same DNA could lead to millions of different mRNAs from which finally antibody molecules are translated. He obtained the Nobel Prize in 1987 as well.

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