Beta-cell development and genetics

Two reviews in Trends in Endocrinology and Metabolism (DOI: http://dx.doi.org/10.1016/j.tem.2014.05.001 and DOI: http://dx.doi.org/10.1016/j.tem.2014.03.013) address the development and the pathogenesis of pancreatic β-cells. Conrad, Stein and Hunter describe the transcription factors in mice and man which lead to β-cell genesis while Thomsem and Gloyn focus their attention to malfunction leading diabetes mellitus. Both reviews together show the actual status in β-cell research.

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