Dechlorination — how it works

In Science this week there is a paper by Brommer et al. from Berlin and Jena, Germany, who reports the structure of the enzyme dehalogenase from
Sulfurospirillum multivorans in complex with trichlorethane and a pseudo-vitamine B12 providing the cobalt ion for electron transfer. A Perspectives article by E.A. Edwards further explains the findings: the pseudo-vitamine B12 is protected from the outside by the dehalogenase and a channel of open for the substrate and its analog.

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